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Artificial Intelligence in New Cardiac MR Markers for Congenital Heart Disease

NCT05979870 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2025-05-15

No results posted yet for this study

Summary

The goal of this study is to investigate children with aortic and pulmonary valve disease treated or untreated longitudinally. Established CMR measures with additional newly developped, promising, highly refined and clinically applicable quantitative imaging biomarkers, will be utilized as compared to the conventional CMR estimates.

The main question\[s\] it aims to answer are:

* \[question 1\]To evaluate risk stratification for surgery and intervention of the aortic- and pulmonary valve
* \[question 2\]Investigate the cardiac and vascular hemodynamic and morphological changes before and after interventional or surgical treatment of the aortic- and pulmonary valve at short and long term.

Participants will undergo cardiac MRI before and after interventional or surgical treatment of the aortic or pulmonary valve Researchers will compare MRI data to an age matched control group established at the department in another study.

Conditions

  • Aortic Valve Disease
  • Pulmonary Valve Disease
  • Child, Only
  • Magnetic Resonance Imaging
  • Risk Stratification

Interventions

PROCEDURE

Valvuloplasty,

Choice of type of intervention decided on a multidisciplinary conference

Sponsors & Collaborators

  • Sahlgrenska University Hospital

    lead OTHER

Principal Investigators

  • Charlotte de Lange, MD, Assoc. Prof · Sahlgrenska University hospital, Queen Silvia Childrens' Hospital

Eligibility

Min Age
1 Week
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-01
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05979870 on ClinicalTrials.gov