A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
NCT05976165 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2026-02-12
Summary
Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.
Conditions
- Gastroesophageal Reflux
- Regurgitation
- Heartburn
Interventions
- OTHER
-
Breath Testing
Subjects drink a small carbohydrate solution, and then provide a breath sample every 15 minutes for one hour, and then every 30 minutes for the next two hours
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Andree Koop, MD · Mayo Clinic
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-11-17
- Primary Completion
- 2027-01-01
- Completion
- 2027-01-31
Countries
- United States
Study Locations
More Related Trials
-
Should I Continue Taking My Acid Reflux Medication? Development and Pilot Testing of a Patient Decision Aid
NCT02558049 ·Status: COMPLETED ·Phase: NA
-
Symptom Control Satisfaction With Proton Pump Inhibitor Regimen
NCT02623816 ·Status: COMPLETED ·Phase: PHASE4
-
Intestinal Microbiota After PPI Treatment
NCT07036627 ·Status: NOT_YET_RECRUITING
-
To Learn How Bone Structure and Bone Mass Change After Long-term PPI Use
NCT01306799 ·Status: COMPLETED
-
A Study to Evaluate the Effects of Food and Esomeprazole on the Pharmacokinetics of Crizotinib in a Coated Microsphere Formulation.
NCT03137134 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Effect of JNJ-67953964 on Gastric Mucosal Integrity in Healthy Male and Female Participants
NCT04185051 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults
NCT02844621 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Randomized Multi-Intervention Trial to Inhibit Precancerous Gastric Lesions in Lingu, Shandong Province
NCT00339768 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot Study To Investigate The Association Between Acid Control And Heartburn Symptoms After Proton Pump Inhibitor Treatment
NCT02708355 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Compare Gastric Inhibition of Two Proton Pump Inhibitors (CL2008-18)(P07815)(COMPLETED)
NCT01005719 ·Status: COMPLETED ·Phase: PHASE3
-
Is Long-Term Proton Pump Inhibitor Use a Cause of Leaky Gut Syndrome
NCT06268834 ·Status: COMPLETED ·Phase: NA
-
A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)
NCT03561090 ·Status: TERMINATED ·Phase: PHASE3
-
A Study to Evaluate the Effect of Food, Formulation, and a Proton Pump Inhibitor (PPI) on Calderasib (MK-1084) in Healthy Adult Participants (MK-1084-003)
NCT06619314 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healthy Participants
NCT07329972 ·Status: COMPLETED ·Phase: PHASE1
-
PPI Test in GP Patients
NCT00318084 ·Status: COMPLETED ·Phase: PHASE4
-
13-C Urea Breath Test Using BreathID System and PPIs (Proton Pump Inhibitors)
NCT00825630 ·Status: COMPLETED ·Phase: PHASE4
-
A Study To Evaluate The Effects Of Repeat Dosing Of Esomeprazole On The Pharmacokinetics Of SB-751689 In Healthy People
NCT00508534 ·Status: COMPLETED ·Phase: PHASE1
-
Study Evaluating Pantoprazole in Adolescents With GERD
NCT00367614 ·Status: COMPLETED ·Phase: PHASE3
-
Drug Drug Interaction Study Of Crizotinib With Esomeprazole.
NCT01549574 ·Status: COMPLETED ·Phase: PHASE1
-
Study Evaluating The Potential Effect Of Lansoprazole On The Pharmacokinetics Of Bosutinib In Healthy Subjects
NCT00952913 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of Rebound Effect After Withdrawal of Proton Pump Inhibitor in Geriatric Population
NCT03467893 ·Status: COMPLETED
-
Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And Food
NCT02097329 ·Status: COMPLETED ·Phase: PHASE1
-
Risk of Cancer Among Pantoprazole Users
NCT01322633 ·Status: COMPLETED
-
Trial of Oral Versus Intravenous Proton Pump Inhibitor on Intragastric pH in Patients With Bleeding Ulcers
NCT00573924 ·Status: COMPLETED ·Phase: NA
-
Effect of Daily Use Proton Pump Inhibitors for One Month on Kidney Function
NCT03910647 ·Status: UNKNOWN ·Phase: PHASE2