Clonal Hematopoiesis of Immunological Significance
NCT05969821 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 5000
Last updated 2026-03-23
Summary
Ambispective, national, multicenter observational cohort study aimed at characterizing the satellite dysimmune manifestations of clonal hematopoiesis, including Vexas (Vacuoles, E1 enzyme, X-linked, Autoinflammatory and Somatic) syndrome.
Conditions
- Immune System Diseases
- Autoimmune Diseases
- Inflammation
- Autoinflammatory Diseases
- Vexas Syndrome
- Hematopoiesis Clonal
- Clonal Hematopoiesis of Indeterminate Potential
- Hematologic Diseases
- Myelodysplastic-Myeloproliferative Diseases
- Leukemia Myelomonocytic Chronic
- Myelodysplastic Syndromes
- Myeloproliferative Disorders
- Lymphoproliferative Disorders
- Lymphoma
- Leukemia
- Monoclonal Gammopathy of Undetermined Significance
Interventions
- OTHER
-
observational cohort study
observational cohort study
Sponsors & Collaborators
-
Sorbonne University
collaborator OTHER -
Institut National de la Santé Et de la Recherche Médicale, France
collaborator OTHER_GOV -
Club MINHEMON (MEDECINE INTERNE, HEMATO ET ONCO)
collaborator UNKNOWN -
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Arsene MEKINIAN, MD PhD · Service de médecine interne, Hôpital Saint Antoine, APHP, Paris
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-30
- Primary Completion
- 2036-04-30
- Completion
- 2045-09-30
Countries
- France
Study Locations
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