Natural Killer Cells Function in Patients With Chronic Lymphocytic Leukemia
NCT00934986 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70
Last updated 2011-09-14
Summary
Purpose:
The involvement of Natural Killer cells (NK) in the efficiency of the treatment in lymphoma and the beginning of new therapies based on function and activation of NK, justify an improvement of knowledge about the status of the population of NK (number, function, genic expression) in Chronic Lymphocytic Leukemia (CLL).
Conditions
Interventions
- OTHER
-
Surface expression of functional biomarkers of the NK cell
An extra blood sample of 40 ml is required : * Stage A patient who does not require a treatment: one sample the day of enrollment. * Stage B or C patient who require RFC treatment: sample at D0 of the 1st and 4th cure of RFC, and 3 months after the end of the treatment.
Sponsors & Collaborators
-
Institut Paoli-Calmettes
lead OTHER
Principal Investigators
-
Thérèse AURRAN-SCHLEINITZ, MD · Institut Paoli-Calmettes
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-03-31
- Primary Completion
- 2010-03-31
- Completion
- 2010-09-30
Countries
- France
Study Locations
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