Thromboxane Function in Women With Endometriosis
NCT05962034 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 96
Last updated 2025-05-04
Summary
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are:
* Do women with endometriosis have greater blood pressure and pain responses to a stimulus than healthy women?
* Do women with endometriosis have greater platelet activity than healthy women?
Participants will take aspirin and/or placebo and will:
* perform hand grip exercise and cold pressor tests
* undergo iontophoresis and blood draw
Researchers will compare women with and without endometriosis to see if there is a difference in neurovascular regulation.
Conditions
- Endometriosis
Interventions
- DRUG
-
650 mg aspirin (Acetylsalicylic acid)
- OTHER
-
Placebo
placebo capsule
Sponsors & Collaborators
-
Penn State University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-01-01
- Primary Completion
- 2026-08-01
- Completion
- 2027-08-01
Countries
- United States
Study Locations
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