Endotypic Traits and Obstructive Sleep Apnea Surgery
NCT05953610 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 150
Last updated 2025-06-27
Summary
This study will examine factors associated with outcomes after soft palate surgery and medications (acetazolamide, eszopiclone) that may treat other potential causes of obstructive sleep apnea (loop gain, arousal threshold).
Conditions
Interventions
- DRUG
-
Acetazolamide 500 MG QHS
Acetazolamide
- DRUG
-
Eszopiclone 3 mg QHS
Eszopiclone
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
University of California, Los Angeles
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-01-07
- Primary Completion
- 2028-08-31
- Completion
- 2028-08-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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