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Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion

NCT05945043 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 124

Last updated 2024-02-28

No results posted yet for this study

Summary

The aim of this study is to better understand the relationship between pleural effusions and breathlessness in patients with unilateral pleural effusions and breathlessness who require pleural fluid removal for its management.

Conditions

  • Pleural Effusion

Interventions

OTHER

Surface parasternal eletromyogram

The surface parasternal EMG of participants will be measured pre, immediately post and at days 1 and 7 following pleural fluid removal

OTHER

Surface diaphragm electromyogram

The ipsilateral and contralateral surface diaphragm EMG of participants will be measured pre and immediately post pleural fluid removal

OTHER

Parasternal muscle ultrasound

The thickness of the parasternal intercostal muscle of participants will be measured using thoracic ultrasound pre and immediately post pleural fluid removal

OTHER

Breathlessness assessment

The VAS breathlessness score and Dyspnoea-12 questionnaire of participants will be measured pre, immediately post and at days 1 and 7 following pleural fluid removal

Sponsors & Collaborators

  • Guy's and St Thomas' NHS Foundation Trust

    lead OTHER

Principal Investigators

  • Patrick Murphy, MBBS BSc · Guy's and St Thomas' NHS Foundation Trust

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-15
Primary Completion
2024-12-31
Completion
2025-01-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05945043 on ClinicalTrials.gov