MedTrace Logo

Comprehensive Imaging Exam of Convalesced COVID-19 Patients

NCT05920616 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 210

Last updated 2025-06-16

No results posted yet for this study

Summary

COVID-19 is a systemic inflammatory disease involving many organs including the lungs, vascular system liver and myocardium that lead to severe pathologies. Patients with severe cardiopulmonary symptoms usually require weeks to months to fully recover. Studies of clinical and subclinical impairments of COVID-19 patients are important for medical practice and public health as well as providing pathogenic insight to the viral infection and secondary immune response. Chronic damage of vital organs and systems, and the potential long-term effects is of serious concern. In this study the investigators plan to quantify and characterize chronic consequences of COVID-19 in individuals who receive similar medical care related to disease severity and duration in a single health care system. Using state-of-the-art Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) technology, we will study the pathology in major organ systems in comparison to matched controls. The results of this study may facilitate measures to prevent, detect, and manage complications from COVID-19 infections.

Conditions

Interventions

OTHER

Magnetic Resonance Imaging

Completion of Magnetic Resonance Imaging of the brain, heart, lungs, and liver with and without contrast.

OTHER

Ultra-High Resolution Computed Tomography (CT) Scan

Completion of a high resolution CT scan of the lungs and high resolution CT of the coronary arteries.

Sponsors & Collaborators

Principal Investigators

  • Joao Lima, MD · Johns Hopkins School of Medicine

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-14
Primary Completion
2025-02-25
Completion
2026-10-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05920616 on ClinicalTrials.gov