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SPECT-CT vs MRI for the Diagnosis of Osteoarthritis in the Foot and Ankle

NCT05912153 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 132

Last updated 2026-02-27

No results posted yet for this study

Summary

The diagnose of symptomatic osteoarthritis in the ankle, mid- and hind foot remains challenging. There is no gold standard for the work-up and various hospitals use different protocols. Current literature shows a promising role for SPECT-CT imaging in ankle, hind- and midfoot OA. In a previous study investigating the role of SPECT-CT in a reproducible group we have observed a change in diagnosis in 53% when SPECT-CT data was added to the data of conventional workup alone. In 26% of patients addition of SPECT-CT data resulted in change of the original treatment plan. To our knowledge no prospective studies are available on this subject for both SPECT-CT and MRI. In our clinic both SPECT-CT and MRI are used in the work-up for patients with ankle, hind- and midfoot pain. Although we experience good result with SPECT-CT, MRI might be able to detect symptomatic OA as well. Moreover MRI provide more information about soft tissue and is less harmful for the patient in comparison to SPECT-CT. The aim of this study is to determine the diagnostic performance of SPECT-CT and MRI when used routinely in patients with symptomatic OA of the ankle, hind- and midfoot.

Conditions

Interventions

DIAGNOSTIC_TEST

SPECT/CT

SPECT/CT of the foot and ankle

DIAGNOSTIC_TEST

MRI

MRI of the foot and ankle

Sponsors & Collaborators

  • Martini Hospital Groningen

    lead OTHER

Principal Investigators

  • Tom van Raaij, MD/PhD · Martini Ziekenhuis

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-04
Primary Completion
2026-12-01
Completion
2027-12-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05912153 on ClinicalTrials.gov