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Prospective Study of Diagnostic Accuracy of Spectral CT for the Detection of Bone Marrow Edema

NCT04963127 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 800

Last updated 2023-11-22

No results posted yet for this study

Summary

Dual-Energy/Multi-Energy/Spectral-CT can visualize bone marrow edema associated with fractures, however, current scientific evidence is mostly derived from to retrospective analyses. Our prospective study systematically analyzes the diagnostic accuracy of the visualization of bone marrow edema by including patients who are scheduled for a CT scan to exclude or further characterize a fracture. After giving informed consent, the CT scan will be performed using a dose-neutral Dual-Energy-/Multi-Energy-/Spectral-CT acquisition technique. If the patient undergoes MRI of the same region within 7 days, this scan will be used as a gold-standard for bone marrow edema. This will allow the quantification of diagnostic accuracy.

Conditions

  • Fractures, Bone
  • Bone Marrow Edema

Interventions

DIAGNOSTIC_TEST

Computed Tomography of the skeleton using a Dual-Energy-/Multi-Energy-/Spectral acquisition mode

CT acquisition using a Dual-Energy / Multi-Energy / Spectral acquisition mode

DIAGNOSTIC_TEST

Computed Tomography of the skeleton using a conventional single-energy / non-spectral acquisition mode

CT acquisition using a standard single energy / non-spectral acquisition mode

Sponsors & Collaborators

  • University Hospital Augsburg

    lead OTHER

Principal Investigators

  • Schwarz, MD · University Hospital Augsburg

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-15
Primary Completion
2025-05-31
Completion
2025-05-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04963127 on ClinicalTrials.gov