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Study on Dynamic Environmental Exposome of ICU and the Establishment of Microbial Transmission Model Between Environment and Host

NCT05877625 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 180

Last updated 2023-06-22

No results posted yet for this study

Summary

HAI (Hospital-acquired infection) is very common in ICU，and lack of understanding of environmental exposure omics and environment-host microbial interactions restricts the prevention and control of HAI. In this project, the investigators try to analyze the spatial and temporal distribution characteristics and evolution of microorganisms and their functions in the ICU environment through metagenome.

Conditions

  • Hospital Acquired Infection
  • Ventilator-associated Pneumonia

Interventions

PROCEDURE

Expectoration care

1. Endotracheal aspiration: from discarded samples after expectoration care 2. BALF (bronchoalveolar lavage fluid): if patients with fiber bronchoscope examination, take the rest of the BALF after examination 3. Oropharyngeal swabs

Sponsors & Collaborators

  • Zhejiang University

    collaborator OTHER

  • Central South University

    collaborator OTHER

  • Peking University Third Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-01
Primary Completion
2023-07-31
Completion
2023-08-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05877625 on ClinicalTrials.gov