Screening for Risk Factors of Prediabetes Among Adult Patients at Sohag University Hospital

Summary

* Prediabetes is an intermediate state of hyperglycemia with glycemic parameters above normal but below the diabetes threshold..
* during the average 3 years of follow-up Prediabetes is diagnosed based on laboratory tests: fasting plasma glucose level (100-125 mg/dl) ;HbA1c, (5.7-6.4%) or plasma glucose level after an oral glucose tolerance test ( 140-199 mg/dl).
* Reports estimate that more than 470 million people will have prediabetes by 2030.
* According to an expert panel of the American Diabetes Association, up to 70% of individuals with prediabetes will eventually develop diabetes.
* Observational evidence suggests as association between prediabetes and complications of diabetes such early nephropathy(10%) , small fiber neuropathy(18-25 %), early retinopathy (8-12%) and risk of macrovascular disease (52%) .
* Screening for prediabetes is designed to save lives or enhance an individual's quality of life by early detection so that screening will minimize the risk of developing diabetes or its complications .

Conditions

• PreDiabetes

Interventions

DIAGNOSTIC_TEST

HbA1c

HbA1c will be measured for all patients to minimize the risk of developing diabetes or its complications .

DIAGNOSTIC_TEST

lipid profile

lipid profile will be measured for all patients to minimize the risk of developing diabetes or its complications .

DIAGNOSTIC_TEST

CBC

CBC will be measured for all patients to minimize the risk of developing diabetes or its complications

DIAGNOSTIC_TEST

Alb/cr ratio

Alb/cr will be measured for all patients to minimize the risk of developing diabetes or its complications

DIAGNOSTIC_TEST

serum creatinine .

serum creatinine will be measured for all patients to minimize the risk of developing diabetes or its complications

DIAGNOSTIC_TEST

CRP

CRP will be measured for all patients to minimize the risk of developing diabetes or its complications

DIAGNOSTIC_TEST

urine analysis

urine analysis will be measured for all patients to minimize the risk of developing diabetes or its complications

DIAGNOSTIC_TEST

ECG

ECG will be done for all patients to minimize the risk of developing diabetes or its complications

DIAGNOSTIC_TEST

fundus examination

fundus examination will be done for all patients to minimize the risk of developing diabetes or its complications

Sponsors & Collaborators

• Sohag University

  lead OTHER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-04-15

Primary Completion

2023-12-31

Completion

2023-12-31

Countries

• Egypt

Study Locations