Digital Multimodal Rehabilitation for People With Post-acute COVID-19 Syndrome.

Summary

Although most infected people survive the infection, many have persistent sequelae or symptoms, which cause disability or decreased quality of life. The World Health Organization has called on countries to prioritize the rehabilitation of the consequences of COVID-19 in both the medium and long term, as this chronicity is expected to impact the health public and the economy in the coming years.

RehabCOVID (also referred to as RehabNautilus) is born from the need to provide solutions to persistent cognitive impairment symptoms of people who have suffered from COVID-19. Thus, we will offer people with long COVID that accomplish inclusion/exclusion criteria to participate in a randomized clinical trial to evaluate the effectiveness of cognitive stimulation therapy combined with physical exercise and mindfulness. The current project is a single-blind randomized control study, where we will compare two combined interventions with a control group that will encompass different functional, structural, and biochemical changes and interactions in the brain. We will study the effects that this combined intervention produces in the brain. We expect to gain more insight into the specific neuroplasticity mechanisms of cognitive persistent COVID symptoms.

Conditions

• Post-COVID Syndrome

Interventions

BEHAVIORAL

RehabCovid_Telematic

A multimodal and digitally-based cognitive training, physical exercise, and mindfulness intervention delivered remotely.

BEHAVIORAL

RehabCovid_ImmersiveVR

A multimodal and digitally-based cognitive training, physical exercise and mindfulness intervention delivered face to face and through 360MK Virtual Reality technology

BEHAVIORAL

Control_Condition

Traditional paper or pdf format multimodal intervention that will combine cognitive, mediation and physical activities.

Sponsors & Collaborators

• University of Barcelona

  collaborator OTHER

• Universitat de Girona

  collaborator OTHER

• Unitat Assistencial i Preventiva de l'Esport- Centre d'Alt rendiment

  collaborator UNKNOWN

• Universitat Politècnica de Catalunya

  collaborator OTHER

• Corporación Fisiogestión

  collaborator UNKNOWN

• Consorci Sanitari de Terrassa

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

100 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-05-05

Primary Completion

2024-12-20

Completion

2024-12-31

Countries

• Spain

Study Locations