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Testicular Tissue Cryopreservation in the Setting of Gender-Affirming Therapy

NCT05829928 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2025-08-07

No results posted yet for this study

Summary

The goal of this study is to learn about fertility preservation in the gender-diverse community. The main objectives it aims to understand are to:

1. Optimize techniques for processing and cryopreserving testicular tissue.
2. Determine presence and number of germ cells (sperm precursors) in the patients' testicular tissue.
3. Develop next generation cell- and tissue-based therapies for preserving fertility and treating infertility.

Conditions

  • Gender Dysphoria
  • Transgender

Interventions

DIAGNOSTIC_TEST

Infectious Disease Testing

Participants will undergo infectious disease testing.

PROCEDURE

Gonadal Tissue Removal

Removal of gonadal tissue will be done through a surgical procedure.

Sponsors & Collaborators

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • Kyle Orwig, PhD · University of Pittsburgh/ University of Pittsburgh Medical Center

Eligibility

Min Age
9 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-05-09
Primary Completion
2029-05-31
Completion
2029-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05829928 on ClinicalTrials.gov