MedTrace Logo

Incidence, Impact and Mechanisms of Perioperative Right VEntricular Dysfunction (IMPRoVE)

NCT05827315 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 175

Last updated 2023-04-25

No results posted yet for this study

Summary

A study to see how common right heart failure (right ventricular dysfunction) after major surgery is, and to investigate if right ventricular dysfunction causes worse patient outcomes after surgery.

Conditions

  • Right Ventricular Dysfunction

Interventions

DIAGNOSTIC_TEST

Echocardiography

Echocardiography will be performed by BSE accredited echocardiographers in all 175 patients preoperatively and on day 2-4 postoperatively.

DIAGNOSTIC_TEST

T1 Cardiovascular Magnetic Resonance

T1 CMR will be performed in 10 patients from each of the 5 surgical groups (50 patients in total) preoperatively and on day 2-4 postoperatively.

DIAGNOSTIC_TEST

Right heart catheterisation and coronary sinus blood sampling

10 patients from the thoracic surgical group will undergo right heart catheterisation and coronary sinus blood sampling.

Sponsors & Collaborators

  • University of Glasgow

    collaborator OTHER

  • NHS Greater Glasgow and Clyde

    collaborator OTHER

  • Royal London Hospital

    collaborator UNKNOWN

  • NHS National Waiting Times Centre Board

    lead OTHER

Principal Investigators

  • Ben Shelley · National Waiting Times Centre Board

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-30
Primary Completion
2026-04-30
Completion
2026-04-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05827315 on ClinicalTrials.gov