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T-Cell Mitochondrial Respiration Response to Ketone Monoester Supplement in Healthy Volunteers and COVID-19

NCT05798260 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2024-06-03

No results posted yet for this study

Summary

T-Cell Mitochondrial Respiration Response to Ketone monoester (Ketoneaid) in Healthy Volunteers and COVID-19

Conditions

  • COVID-19 Acute Respiratory Distress Syndrome

Interventions

DIAGNOSTIC_TEST

Agilent Seahorse XF Cell Mito Stress Test

The Agilent Seahorse XF Cell Mito Stress Test measures key parameters of mitochondrial function by directly measuring the oxygen consumption rate (OCR) of cells on the Seahorse XFe and XF Extracellular Flux Analyzers. It is a plate-based live cell assay that allows to monitor spare respiratory capacity (SRC), basal respiration, ATP production-coupled respiration, maximal respiration, and non-mitochondrial respiration in real time before and after ketone monoester

Sponsors & Collaborators

Principal Investigators

  • Christina Barkauskas, MD · Research Director Duke Medical ICU

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-06-30
Primary Completion
2024-08-31
Completion
2024-10-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05798260 on ClinicalTrials.gov