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Assessment of Oxygen Extraction Rate Changes Following Red Blood Cell Transfusion in the Intensive Care Unit

NCT05798130 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 88

Last updated 2024-03-12

No results posted yet for this study

Summary

Restrictive and liberal approaches to hemoglobin targets are used when deciding on red blood cell transfusions in patients who do not have acute bleeding and have a hemodynamically stable course in the intensive care unit. However, physiologic trigger points that assess tissue oxygenation when deciding on blood transfusion in patients are also among the important topics of study in recent years. In this study, the investigators will evaluate the oxygen extraction rate, which is an important indicator of the balance between tissue oxygen delivery and consumption. Whether oxygen extraction rate can be used as a trigger for blood transfusion will be determined by clinical outcomes in ICU patients. If physiologic transfusion targets are feasible, the risks of unnecessary transfusions can be avoided with individualized targets, and the decision to transfuse blood can be made without delay in patients requiring red blood cell transfusion.

Conditions

  • Red Blood Cell Transfusion
  • Oxygen Consumption

Interventions

OTHER

No intervention group.

No intervention group.

Sponsors & Collaborators

  • Izmir Katip Celebi University

    lead OTHER

Principal Investigators

  • Ahmet Salih Tüzen · Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Anesthesiology and Reanimation

  • Murat Aksun · Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Anesthesiology and Reanimation

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-01
Primary Completion
2023-09-30
Completion
2023-12-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05798130 on ClinicalTrials.gov