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Three-pronged Centralized Molecular Analysis to Optimize Detection of NTRK1,2,3 Fusions in Thyroid Cancer

NCT05796258 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2024-12-05

No results posted yet for this study

Summary

This multi-center study aims at NTRK fusion testing of all patients with advanced thyroid cancer (any histotype and regardless of stage). The primary objective of this study is to assess the frequency of NTRK fusions in thyroid cancer. The secondary objective of this study is to develop an effective tool (testing) strategy for the detection of NTRK fusions in thyroid tumors, comparing the diagnostic tecniques available (IHC, real-time PCR and NGS).

Conditions

Interventions

DIAGNOSTIC_TEST

NTRK fusion assessment

To evaluate NTRK fusion presence by MCG, Immunohistochemistry or NGS

Sponsors & Collaborators

  • University of Roma La Sapienza

    collaborator OTHER

  • Bambino Gesù Hospital and Research Institute

    collaborator OTHER

  • Regina Elena Cancer Institute

    lead OTHER

Principal Investigators

  • Marialuisa Appetecchia, Prof · Regina Elena Cancer Institute

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-26
Primary Completion
2023-12-31
Completion
2024-12-04

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05796258 on ClinicalTrials.gov