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Study of the Medullary Microenvironment in Acute Childhood Leukemia

NCT05792007 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2025-11-24

No results posted yet for this study

Summary

Acute leukemia (AL) is the most common cancer in children. Despite the optimization of chemotherapy treatments and the development of supportive care, a certain number of LAs relapse and/or progress to death of the child. It therefore seems essential to try to better understand the physiopathology and the mechanisms of resistance to treatment of these diseases.

Conditions

  • Acute Lymphoid Leukemia
  • Acute Myeloid Leukemia in Children

Interventions

PROCEDURE

Biological sampling in patients

blood and bone marrow samples from patients with Acute Leulemia.

PROCEDURE

Biological sampling in control patients

blood and bone marrow samples from children undergoing orthopedic surgery exposing the bone marrow.(osteotomy of the pelvis).

Sponsors & Collaborators

  • University Hospital, Tours

    lead OTHER

Principal Investigators

  • Olivier HERAULT, MD-PhD · University Hospital of TOURS

  • Julien LEJEUNE, MD-PhD · University Hospital of TOURS

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
1 Year
Max Age
15 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-26
Primary Completion
2026-10-25
Completion
2028-10-24

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05792007 on ClinicalTrials.gov