Anti-Leukemia Immune Responses After Irradiation of Extramedullary Tumors
NCT05035706 · Status: ACTIVE_NOT_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2026-03-05
Summary
This clinical trial assesses how the immune system responds to leukemia tumors after low dose radiation delivered as part of standard of care. The information learned in this study may help them know if adding immunotherapy (a type of treatment that uses the immune system to fight cancer) can be helpful in future leukemia patients receiving radiation.
Conditions
- Acute Myeloid Leukemia
- Myeloid Leukemia
- Recurrent Acute Myeloid Leukemia
Interventions
- PROCEDURE
-
Biopsy
Undergo biopsy
- PROCEDURE
-
Biospecimen Collection
Undergo blood and tissue sample collection
- OTHER
-
Electronic Health Record Review
Medical records reviewed
- OTHER
-
Photography
Photographs taken
Sponsors & Collaborators
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Bouthaina S Dabaja · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-06-30
- Primary Completion
- 2026-04-30
- Completion
- 2026-04-30
Countries
- United States
Study Locations
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