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Comparative Metabolomics in Diabetes Patients From Sri Lanka and Switzerland

NCT05787457 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2023-03-28

No results posted yet for this study

Summary

This study is a case-control study, where the assumed different subtypes of type 2 diabetes in people of Tamil ethnicity and Swiss origin living in Bern, Switzerland will be examined by measuring the metabolite profiles and the corresponding genetic background as well as ethnic differences in fat distribution performed by magnetic resonance imaging (MRI). The investigators aim to show that the specific metabolite profile and the fat distribution in the Tamil population is associated with the high prevalence of diabetes in this ethnicity. Fat distribution patterns are thought to determine the expression and severity of dysglycaemia. Additionally, the investigators aim to identify the key enzymes, their corresponding genes, and the respective polymorphisms relevant for these metabolic variations.

Conditions

  • Diabetes Mellitus, Type 2

Interventions

OTHER

Clinical examination

OTHER

Blood testing

OTHER

MRI

Sponsors & Collaborators

  • Insel Gruppe AG, University Hospital Bern

    lead OTHER

Principal Investigators

  • Martin Fiedler, MD, MBA · Insel Gruppe AG, University Hospital Bern

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-07-31
Primary Completion
2021-09-30
Completion
2021-09-30

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05787457 on ClinicalTrials.gov