Carotid Body Function in Type 2 Diabetes Mellitus
NCT05237076 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2023-05-31
Summary
This trial will assess chemosensitivity differences of the carotid bodies in individuals with T2DM, compared to healthy controls. During baseline and hyperinsulinemia.
Conditions
- Diabetes Mellitus, Type 2
- Hypoxia
Interventions
- DIAGNOSTIC_TEST
-
Hyperinsulemic-Euglycemic Clamp & Hypoxic Ventilatory Response (HVR)
Hyperinsulemic-Euglycemic Clamp as described by deFronzo et al.
Sponsors & Collaborators
-
Demcon
collaborator INDUSTRY -
Leiden University Medical Center
lead OTHER
Principal Investigators
-
Albert Dahan, MD, PhD · LUMC
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-12-01
- Primary Completion
- 2022-08-05
- Completion
- 2023-02-15
Countries
- Netherlands
Study Locations
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