Cluster-Randomized Trial of Air Filtration and Ventilation to Reduce Covid19 Spread in Homes

NCT05777720 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 214

Last updated 2026-02-19

No results posted yet for this study

Summary

Investigators are evaluating whether an intervention consisting of box-fans with MERV 16 filters ("filtration fans") and recommendations for improving ventilation in the home can reduce secondary spread of Covid19 from an index case to susceptible contacts within the home.

Conditions

  • Covid19

Interventions

DEVICE

Filtration Fan

Investigators are using box fans with attached MERV16 filters, a design that has been tested and published in the scientific literature.

BEHAVIORAL

Safe-home pamphlet

The pamphlet has information on how the filtration fans work through visual images; and images of ventilation improvements in the home through opening windows.

BEHAVIORAL

Mid-week phone call

On day 3-4 of the study, the study coordinator assigned to the house will call and check in regarding the filtration fan usage and remind families about the importance of filtration and ventilation.

Sponsors & Collaborators

  • National Institute of Allergy and Infectious Diseases (NIAID)

    collaborator NIH
  • Stanford University

    lead OTHER

Principal Investigators

  • Yvonne Maldonado, MD · Stanford University

  • Abraar Karan, MD · Stanford University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-30
Primary Completion
2025-12-30
Completion
2025-12-30

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05777720 on ClinicalTrials.gov