LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers

Summary

The study is a follow-up of a Randomized Controlled Trial (RCT) performed in 2007-10 - the "Lifestyle in Pregnancy" LiP study.

The LiP study included 360 pregnant women with BMI ≥30 kg/m2 from Odense University Hospital and Aarhus University Hospital. The women were randomized to intervention with low-calorie diet and physical activity from gestational age 10-14 in pregnancy and until delivery - or to a standard care control group. The objective of the LiPO-Teen project is to perform a clinical follow-up study of the eligible 301 mothers who completed the trial until delivery with a liveborn child, and their 14 year-old offspring. The overall ambition is to understand whether lifestyle intervention in pregnancy prevents obesity and its complications across generations, with a specific focus on modifiable factors.

Conditions

• Obesity
• Life Style, Healthy
• Follow-up
• Gestational Weight Gain
• Body Weight

Interventions

BEHAVIORAL

Lifestyle intervention Dietary advise and/or advise on physical activity

Lifestyle intervention Dietary advise and/or advise on physical activity

Sponsors & Collaborators

• Steno Diabetes Center Odense

  collaborator OTHER

• University of Southern Denmark

  collaborator OTHER

• Statens Serum Institut

  collaborator OTHER

• University of Aarhus

  collaborator OTHER

• Aarhus University Hospital

  collaborator OTHER

• Odense University Hospital

  lead OTHER

Principal Investigators

• Christina A Vinter, M.D. Ph.D. · Department of Gynecology and Obstetrics. Odense University Hospital. University of Southern Denmark

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

13 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-10-26

Primary Completion

2025-12-01

Completion

2026-03-01

Countries

• Denmark

Study Locations