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Efficacy of Parecoxib Combined With Paracetamol in Mastectomy

NCT05757388 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2023-04-14

No results posted yet for this study

Summary

Patients undergoing breast cancer surgery experience persistent pain after surgery and subsequent development of chronic pain. Parecoxib or paracetamol has been reported to reduce postoperative pain in mastectomy. The investigators aim to assess the effectiveness of the perioperative administration of parecoxib combined with paracetamol to reduce postoperative acute and subacute breast surgical pain.

Conditions

  • Post Operative Pain

Interventions

DRUG

Parecoxib + paracetamol

Administers after induction of anesthesia.

DRUG

Normal saline

Administers after induction of anesthesia.

Sponsors & Collaborators

  • Khon Kaen University

    lead OTHER

Principal Investigators

  • Thepakorn Sathitkarnmanee, MD · Khon Kaen University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-28
Primary Completion
2023-05-01
Completion
2023-05-10

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05757388 on ClinicalTrials.gov