Combination of SON-1010 (IL12-FHAB) and Atezolizumab in Patients With Platinum-resistant Ovarian Cancer
NCT05756907 · Status: TERMINATED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2026-02-03
Summary
This is a Phase 1b/2a, open-label, adaptive-design outpatient study to assess the safety, tolerability, and PK/PD of SON-1010 in combination with atezolizumab administered to patients with advanced solid tumors (Part 1) and patients with Platinum-resistant Ovarian Cancer (Part 2)
Conditions
- Advanced Solid Tumor
- Platinum-resistant Ovarian Cancer
Interventions
- BIOLOGICAL
-
SON-1010
SON-1010 + Atezolizumab
Sponsors & Collaborators
- collaborator INDUSTRY
-
Sonnet BioTherapeutics
lead INDUSTRY
Principal Investigators
-
Richard T Kenney, MD · Sonnet BioTherapeutics
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-09-15
- Primary Completion
- 2025-12-31
- Completion
- 2026-01-08
- FDA Drug
- Yes
Countries
- United States
- Australia
Study Locations
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