A Study of MM-121 With Paclitaxel in Platinum Resistant/ Refractory Advanced Ovarian Cancers
NCT01447706 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 223
Last updated 2016-05-12
Summary
To determine whether the combination of MM-121 plus paclitaxel is more effective than paclitaxel alone
Conditions
- Epithelial Ovarian Cancer
- Fallopian Tube Cancer
- Peritoneal Cancer
Interventions
- DRUG
-
MM-121
MM-121 (SAR256212) (IV)
- DRUG
-
Standard dosing Paclitaxel (IV)
Sponsors & Collaborators
- collaborator INDUSTRY
-
Merrimack Pharmaceuticals
lead INDUSTRY
Principal Investigators
-
Victor Moyo, MD · Merrimack Pharmaceuticals
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-10-31
- Primary Completion
- 2013-09-30
- Completion
- 2015-06-30
Countries
- United States
Study Locations
More Related Trials
-
Paclitaxel and Carboplatin With Or Without Sorafenib In The First-Line Treatment Of Patients With Ovarian Cancer
NCT00390611 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel in Treating Patients With Recurrent or Persistent Ovarian or Primary Peritoneal Cancer
NCT00005046 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Paclitaxel (Albumin-bound) Combination With Carboplatin in Ovarian Cancer.
NCT04661696 ·Status: UNKNOWN ·Phase: PHASE2
-
Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers
NCT02020707 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Relacorilant in Combination With Nab-Paclitaxel for Patients With Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT03776812 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial Evaluating the Efficacy and Safety of ZL-2306 (Niraparib) in Ovarian Cancer Patient
NCT03705156 ·Status: UNKNOWN ·Phase: PHASE3
-
Treatment of Paclitaxel Plus Carboplatin Followed by Gemcitabine Plus Carboplatin for Patients With Epithelial Ovarian Cancer
NCT00490711 ·Status: COMPLETED ·Phase: PHASE2
-
An Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian Cancer
NCT00738699 ·Status: TERMINATED ·Phase: PHASE2
-
Anlotinib Combined With Carboplatin/Paclitaxel as First-line Treatment in Patients With Advanced Ovarian Cancer
NCT04807166 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of AMG 386 in Combination With Paclitaxel and Carboplatin in Subjects With Ovarian Cancer
NCT01253681 ·Status: COMPLETED ·Phase: PHASE1
-
Paclitaxel, Polyglutamate Paclitaxel, or Observation in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Peritoneal Cancer, or Fallopian Tube Cancer
NCT00108745 ·Status: UNKNOWN ·Phase: PHASE3
-
Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Persistent or Recurrent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
NCT01468909 ·Status: COMPLETED ·Phase: PHASE2
-
ONC201 Plus Weekly Paclitaxel in Patients With Platinum Refractory or Resistant Ovarian Cancer
NCT04055649 ·Status: RECRUITING ·Phase: PHASE2
-
Oxaliplatin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Has Not Responded to Platinum- Based Chemotherapy
NCT00005836 ·Status: COMPLETED ·Phase: PHASE2
-
Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65).
NCT05116189 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Albumin-bound Paclitaxel and Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer
NCT05310344 ·Status: UNKNOWN ·Phase: PHASE2
-
Cisplatin and Paclitaxel in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer
NCT00814086 ·Status: COMPLETED ·Phase: PHASE1
-
Apatinib With Albumin-bound Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer
NCT03942068 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase Ib/Ⅱ Clinical Trial of LBL-024 Combined With Paclitaxel in Patients With Platinum-resistant Ovarian Cancer
NCT07042802 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Weekly Infusions of Paclitaxel in Treating Women With Stage III or Stage IV Ovarian Cancer Refractory to Paclitaxel and Platinum
NCT00003160 ·Status: UNKNOWN ·Phase: PHASE2
-
Pazopanib Hydrochloride, Paclitaxel, and Carboplatin in Treating Patients With Refractory or Resistant Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
NCT01402271 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Platinum-based Chemotherapy With or Without Paclitaxel in Treating Patients With Relapsed Ovarian Cancer
NCT00002894 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Fluzoparib±Apatinib Versus Placebo Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on First-Line Platinum-Based Chemotherapy
NCT04229615 ·Status: UNKNOWN ·Phase: PHASE3
-
Neoadjuvant Chemotherapy IV Carboplatin With Weekly Paclitaxel \Bevacizumab for Primary Ovarian
NCT01219777 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer
NCT01081262 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3