MedTrace Logo

Active Screening of Latent Tuberculosis Infection in School Contacts of Active Tuberculosis Patients

NCT06033807 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 31440

Last updated 2025-04-01

No results posted yet for this study

Summary

The goal of this observational study is to investigate the proportion of Mycobacterium tuberculosis (MTB) infection in school contacts of active tuberculosis (ATB) patients. The main questions it aims to answer are:

* the proportion of MTB infection among school contacts of ATB patients
* risk factors related to tuberculosis (TB) infection
* health economic evaluation of screening strategy

Conditions

Interventions

DIAGNOSTIC_TEST

QuantiFERON-TB Gold (QFT) test

Participants will be tested by QuantiFERON-TB Gold (QFT) test to see if they have ever infected by MTB. Those with positive results will proceed to sputum Xpert MTB/RIF, physical examination and chest CT scan, as well as sputum culture if necessary to distinguish latent TB infection (LTBI) from ATB. X-ray scan is conditional on age above 15 years with a positive QuantiFERON-TB Gold (QFT) test result.

Sponsors & Collaborators

  • Guizhou Center for Disease Control and Prevention

    collaborator OTHER

  • Huashan Hospital

    lead OTHER

Principal Investigators

  • Wenhong Zhang, PhD · Huashan Hospital

Eligibility

Min Age
13 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2025-09-01
Completion
2025-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06033807 on ClinicalTrials.gov