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Determination of Nerve Growth Factor (NGF) Expression in Pediatric Patients With Severe Burns: a Pilot Study

NCT05751174 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2023-03-02

No results posted yet for this study

Summary

The goal of this observational study is to determine the blood values of NGF in severely burned patients, to describe any changes over time and finally to correlate the expression of NGF to the severity of the burn.

The main question it aims to answer is:

\- describe NGF values in severely burned pediatric patients and to evaluate their correlation with the severity of the burn and the extent of the burned skin surface by measuring the circulating levels of NGF in pediatric patients.

Participants will undergo blood sampling on days 2,7,14 and 30 after the traumatic event for the clinical follow-up envisaged by the internal protocol.

Conditions

  • Burns

Interventions

OTHER

pediatric patients affected by severe burns

All patients admitted to the pediatric intensive care unit affected by severe burns involving more than 10% of the body surface will be enrolled.

Sponsors & Collaborators

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    lead OTHER

Principal Investigators

  • Giorgio GC Conti, Professor · Fondazione Policlinico Gemelli IRCCS, Rome

Eligibility

Min Age
1 Month
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-18
Primary Completion
2022-05-26
Completion
2022-08-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05751174 on ClinicalTrials.gov