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Potential Prognostic Markers of Recovery in Post-stroke Rehabilitation

NCT05750303 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 32

Last updated 2023-03-01

No results posted yet for this study

Summary

Despite increasingly effective early treatment strategies for ischemic stroke, post-stroke recovery is often incomplete and depend on spontaneous and therapeutic-induced processes related to neuroplasticity, angiogenesis and reperfusion. These processes are regulated by growth factors, neurotrophines, neurotransmitters, hormones and other factors. This study aims to search biomarkers that prognose brain repair ability and consequently estimate an outcome of stroke patients. The prognostic value of proteins VEGF, IGF-1 and MMP-9 and expression of genes VEGF, IGF-1, MMP-9 is evaluated in association with clinical scales including cognitive assessment scales and depression scales. Blood sample collection as well as scales recording are taken at baseline and 3 weeks later after rehabilitation.

Conditions

Sponsors & Collaborators

  • University of Lodz

    collaborator UNKNOWN

  • Medical University of Lodz

    lead OTHER

Principal Investigators

  • Elzbieta Miller, Prof · Medical University of Lodz

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-02
Primary Completion
2023-01-31
Completion
2023-01-31

Countries

  • Poland

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05750303 on ClinicalTrials.gov