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Procedural Motor Memory in Long COVID-19

NCT05746624 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 333

Last updated 2025-03-30

No results posted yet for this study

Summary

Background:

Most people who get COVID-19 seem to recover with no long-term effects. However, some people who recover from acute COVID-19 infections report lingering symptoms. This is called long COVID. Many people with long COVID report symptoms related to the nervous system; these can include problems with fatigue, speech, and memory.

Objective:

To test motor memory in people with long COVID, compared to healthy volunteers.

Eligibility:

People aged 18 to 90 years who are also enrolled in study protocol 000089. Healthy adults are also needed.

Design:

Participants will be screened by telephone. They will confirm they are able to type without discomfort using their nondominant hand. They will confirm they have access to a computer connected to the internet.

All study tasks will be done online. Participants will complete 2 tasks in 2 days.

Participants will be sent a link to a website. The website will give them instructions. They will place the fingers of their nondominant hand over 4 numbers on the keyboard and type a sequence (eg, 4-1-3-2-4). They will type this sequence as often as they can in 10 seconds. Then they will rest for 10 seconds before repeating the task. They will repeat this pattern for 15 minutes.

After they finish the typing task, participants will take a 10-minute questionnaire. They will answer questions about their experiences with COVID-19 and memory issues; they will say which hand they use for tasks such as brushing their teeth or throwing a ball.

Participants will get a notice to repeat the typing task 22 hours after they finish the first one. They should complete the second task within 28 hours....

Conditions

  • Infectious Metabolic Encephalopathy
  • Ischemic Stroke
  • Seizure
  • Viral Encephalitis, Small and Large Vessel

Interventions

BEHAVIORAL

keypresses

benign behavioral intervention-- keypresses

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    lead NIH

Principal Investigators

  • Leonardo G Cohen, M.D. · National Institute of Neurological Disorders and Stroke (NINDS)

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-15
Primary Completion
2022-03-17
Completion
2022-03-17

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05746624 on ClinicalTrials.gov