Clinical and Biological Characterization of Post COVID-19 Syndrome

Summary

The goal of this observational study is to describe the symptoms that persist for more than 12 weeks after the acute episode in participants who had COVID-19, and compare the functional, socioeconomic and occupational effects with a post-COVID-19 control group without persistent symptoms after the COVID-19 acute event.

The main questions it aims to answer are:

* What are the characteristics of symptoms that persist for more than 12 weeks in participants who have had COVID19 in the last year?
* What are the health-related quality of life and psychosocial effects in participants with persistent symptoms of COVID-19, compared to a post-COVID-19 control group without persistent symptoms after the acute episode of COVID-19?

Conditions

• Long COVID

Interventions

DIAGNOSTIC_TEST

Clinical, mental health and psychosocial profile of Post-COVID-19 syndrome

Evaluation of persistent symptoms of COVID-19 and its association with psychological, cognitive and social status in comparison to a healthy control group

DIAGNOSTIC_TEST

Diagnostic performance of echocardiographic and biological markers in Post-COVID-19 syndrome

Determine the inflammatory, immune profile and ventricular function in post-COVID-19 participants compared to a control group

Sponsors & Collaborators

• Hospital El Cruce

  collaborator OTHER

• National University of Cuyo

  collaborator OTHER

• Universidad Nacional de La Plata

  collaborator OTHER

• University of Buenos Aires

  collaborator OTHER

• Arturo Jauretche National University

  lead OTHER

Principal Investigators

• Laura Antonietti, MD, MHA · Arturo Jauretche National University

• Javier Mariani, MD · Hospital El Cruce

• Walter Manucha, PhD · National University of Cuyo

• Mariela Paz, PhD · University of Buenos Aires

• Martín Rumbo, PhD · Universidad Nacional de La Plata

• Liliana Dain, PhD · University of Buenos Aires

• Carlos Tajer · Hospital El Cruce

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-02-16

Primary Completion

2023-04-30

Completion

2023-06-30

Countries

• Argentina

Study Locations