Follow-up of Covid-19 Long Term Sequelae

Summary

The protocol, in accordance with the objectives of ORCHESTRA project - Work Package 2, aims at investigating the characteristics and determinants of COVID-19 long-term sequelae. This goal will be reached through the harmonization of follow-up strategies across the participating cohorts to allow a standardized collection of data on COVID-19 long-term sequelae. The result will be a platform including a set of data and biomaterials from large scale international cohorts, that will be uniformly recorded, prospectively tracked and analysed. The ultimate goal will be that of providing evidence to contribute to the optimization and improvement of the management and prevention of COVID-19 sequelae.

The follow-up will be organized in multiple levels of tests, according to the capability of each cohort, and will include questionnaires to collect demographic, epidemiological and clinical data, physical examination, radiological exams and biological sampling. The long-term follow-up will also allow the assessment of long-term immunological response to SARS-CoV-2 infection and its association to the vaccination and to different treatment strategies, including monoclonal antibodies.

Conditions

• COVID-19 Pneumonia
• COVID-19 Respiratory Infection
• COVID-19 Acute Bronchitis
• COVID-19 Acute Respiratory Distress Syndrome
• COVID-19 Lower Respiratory Infection
• Covid19
• Corona Virus Infection
• Coronavirus
• Coronavirus Infections
• SARS-CoV2 Infection
• SARS-CoV-2 Acute Respiratory Disease
• SARS-Associated Coronavirus
• SARS Pneumonia
• SARS (Severe Acute Respiratory Syndrome)
• SARS (Disease)
• Coronavirus Pneumonia
• Coronavirus Disease 2019
• Coronavirus Sars-Associated

Interventions

OTHER

Not applicable (observational study)

Not applicable (observational study)

Sponsors & Collaborators

• University of Bologna

  collaborator OTHER

• Institut National de la Santé Et de la Recherche Médicale, France

  collaborator OTHER_GOV

• Universiteit Antwerpen

  collaborator OTHER

• University of Sao Paulo

  collaborator OTHER

• Barcelona Institute for Global Health

  collaborator OTHER

• Fondation pour la Recherche Médicale

  collaborator OTHER

• Andaluz Health Service

  collaborator OTHER_GOV

• Charite University, Berlin, Germany

  collaborator OTHER

• CINECA consorzio universitario italiano

  collaborator UNKNOWN

• University Medical Center Groningen

  collaborator OTHER

• Hospital Universitario Virgen Macarena

  collaborator OTHER

• Azienda Ospedaliera Universitaria Integrata Verona

  lead OTHER

Principal Investigators

• Evelina Tacconelli, Professor · Universita di Verona

Eligibility

Min Age

14 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-04-16

Primary Completion

2024-05-31

Completion

2024-05-31

Countries

• Belgium
• France
• Italy
• Netherlands
• Republic of the Congo
• Spain

Study Locations