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Examining the Impact of Nicotine Pouches in Rural Ohio and Ohio Appalachia

NCT05730439 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 71

Last updated 2026-04-27

No results posted yet for this study

Summary

This clinical trial examines the impact of nicotine patches on preventing cancer in rural and Appalachia Ohio residents. Nicotine pouches are new smokeless tobacco products that are marketed as substitutes for smokeless tobacco and are gaining in popularity. There is little research on how nicotine pouches will be adopted by residents of Ohio Appalachia and rural Ohio. This study may help researchers better understand the appeal and potential impact of nicotine pouches on public health.

Conditions

  • Tobacco-Related Carcinoma

Interventions

PROCEDURE

Biospecimen Collection

Undergo collection of blood

DRUG

Nicotine Oral Pouch

Receive ZYN brand NP

DRUG

Nicotine Oral Pouch

Receive Rogue brand NP

OTHER

Questionnaire Administration

Ancillary studies

DRUG

Smokeless Tobacco

Receive usual SLT

Sponsors & Collaborators

  • Ohio State University Comprehensive Cancer Center

    lead OTHER

Principal Investigators

  • Brittney L Keller-Hamilton, PhD, MPH · Ohio State University Comprehensive Cancer Center

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-19
Primary Completion
2024-01-30
Completion
2024-08-05
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05730439 on ClinicalTrials.gov