MedTrace Logo

Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection

NCT05728710 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 350

Last updated 2023-02-15

No results posted yet for this study

Summary

Endoscopic resection of superficial colorectal neoplasms decrease risk of colorectal cancer. En bloc resection is necessary for large superficial lesions with risk of superficial submucosal cancer and is advised if feasible for all lesions. Endoscopic submucosal dissection (ESD) allows en bloc resection of large superficial colorectal neoplasms, increasing curative resection rate and decreasing local recurrence risk. However, the risk of perprocedural or delayed perforation is higher compared to wild field piece meal endoscopic mucosal resection. Endoscoping clipping and closing methods mostly allow conservative treatment, but some case still necessitate surgery. The aim of our study is to describe and ananalyse outcomes after perprocedural or delayed perforation in all patients undergoing ESD and analyse the need for surgical intervention.

Conditions

  • Colorectal Neoplasms
  • Perforation of Rectum
  • Perforation Colon

Interventions

PROCEDURE

Endoscopic submucosal dissection

standard ESD performed and complicated with a perprocedural or delayed perforation

Sponsors & Collaborators

  • Central Hospital, Nancy, France

    lead OTHER

Principal Investigators

  • Marion Schaefer, MD · Central Hospital, Nancy, France

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-01
Primary Completion
2023-03-31
Completion
2023-04-01

Countries

  • Belgium
  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05728710 on ClinicalTrials.gov