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Prospective Observational Study on the Incidence of Opportunistic Fungal Infections

NCT05707156 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12032

Last updated 2025-04-02

No results posted yet for this study

Summary

Corticosteroids exposure is a common risk factor for invasive fungal infections. Systemic corticosteroid therapy treats several medical conditions, including rejection in solid organ transplant recipients, malignancy, and autoimmune or inflammatory diseases. Corticosteroid exposure is a well-known risk factor for developing PJP. Still, it remains unclear how prior corticosteroid exposure influences the presentation, severity, and mortality of opportunistic fungal infections. The investigators aim to prospectively characterize the corticosteroid use as a dose response to inform risk of invasive fungal infections.

Conditions

  • Pneumocystis Jirovecii Infection
  • Pneumocystis
  • Cryptococcosis
  • Candidiasis
  • Aspergillosis

Sponsors & Collaborators

  • University of Georgia

    collaborator OTHER

  • University of California, Davis

    collaborator OTHER

  • University of Colorado, Denver

    lead OTHER

Principal Investigators

  • ANDRES F HENAO, MD · University of Colorado, Denver

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-05
Primary Completion
2024-01-05
Completion
2024-01-05

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05707156 on ClinicalTrials.gov