Study of Changes and Characteristics of Genes in Patients With Pancreatic Cancer for Better Treatment Selection

NCT02750657 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 332

Last updated 2025-11-18

No results posted yet for this study

Summary

Researchers are looking for better ways of understanding and treating pancreatic cancer. The purpose of this study is to see how useful it is to look for changes and characteristics in your genes (molecules that contain instructions for the development and functioning of the cells) and the genes within the tumour. These characteristics may be useful in choosing treatments for patients in the future. Changes (mutations) in genes have been shown to be an important characteristic in cancers. Looking at differences in genes in patients with advanced pancreatic ductal adenocarcinomas and comparing this information with response to their initial chemotherapy treatment may help to learn which treatments may be better for certain patients after initial treatment.

Conditions

  • Carcinoma, Pancreatic Ductal

Interventions

GENETIC

Molecular Profiling

Whole Genome Sequencing

Sponsors & Collaborators

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • Jennifer J. Knox, M.D. · Princess Margaret Cancer Centre

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-12-31
Primary Completion
2025-08-31
Completion
2025-08-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02750657 on ClinicalTrials.gov