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Prospective Multicenter Cohort Study Evaluating the Incidence and Risk Factors for Problem Gambling Among Young Adults With First-episode Psychosis

NCT05686772 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 520

Last updated 2025-05-28

No results posted yet for this study

Summary

The aims of this propsective cohort study are to get a better understanding of the association between problem gambling and psychotic disorders among young adults with first-episode psychosis.

The main questions to be answered are:

1. What is the incidence of problem gambling in this population?
2. What are the predictors of problem gambling in this population?

To do so, putative predictors of problem gambling will be analyzed using Cox regression models:

* Sociodemographics (e.g., age, gender identity, ethnicity, level of education, employment);
* Psychiatric comorbidities (e.g., substance use disorders, cluster B personality disorders);
* Antipsychotic use (first/second-generation, third-generation \[aripiprazole, brexpiprazole, cariprazine\]);
* Prior gambling history.

Conditions

  • Gambling Disorder
  • Psychotic Disorders

Interventions

DRUG

Antipsychotic use

Use of first/second generation antipsychotics, use of third-generation antipsychotics, use of aripiprazole specifically

OTHER

Psychiatric comorbidities

Substance use disorders, cluster B personality disorders, anxiety disorder, major depressive disorder, attention-deficit/hyperactivity disorder, tobacco smoking

OTHER

Sociodemographics/socioeconomic status

Age, gender identity, ethnicity, highest educational attainment, employment, at school, homelessness, in a relationship

OTHER

Gambling history

Non-problematic gambling at the time of admission and/or previous 12 months

OTHER

Clinical variables

Main psychiatric diagnosis, history of psychiatric hospitalizations, severity of illness (CGI-S), functioning (SOFAS), concomitant psychotropic medications use

Sponsors & Collaborators

  • Fonds de la Recherche en Santé du Québec

    collaborator OTHER_GOV

  • Laval University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-01
Primary Completion
2023-05-01
Completion
2023-05-01

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05686772 on ClinicalTrials.gov