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Vasopressor Support, Mean Arterial Pressure and Capillary Refill Time in Critically Ill Patients

NCT05674084 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2023-01-06

No results posted yet for this study

Summary

The goal of this observational study is to learn whether different doses of various vasopressor drugs influence capillary refill time (CRT) value in crtically ill patients. The main questions it aims to answer are:

* How do vasopressor drugs determine CRT value
* How does mean arterial pressure (MAP) determine CRT value
* How often CRT value is normal (\< 3 sec) despite hypotensive MAP (\<65 mmHg)

Participants will have the CRT measured over the course of the ICU hospitalization. At the end of the study, multiple linear regression will be performed to verify whether different doses of vasopressor drugs influence CRT value.

Conditions

  • Critical Illness

Interventions

DIAGNOSTIC_TEST

Capillary refill time

CRT will be measured by applying firm pressure to the ventral surface of the index finger distal phalanx with a glass microscope slide. The pressure will be increased until the skin is blank and then maintained for 10 seconds. The time for return of the normal skin color will be registered with a chronometer, and \> 3 seconds is defined as abnormal. Light and ambient temperature will be the same for all individuals.

Sponsors & Collaborators

  • Medical University of Silesia

    lead OTHER

Principal Investigators

  • Łukasz Krzych, Professor · Medical University of Silesia

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-12-03
Primary Completion
2023-10-31
Completion
2023-12-31

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05674084 on ClinicalTrials.gov