Correlation Between SPECT/CT and IDH Mutation in Brain Glioma
NCT05595863 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2022-10-27
Summary
Major advances in cancer genetics over the past decade have revealed that the genes encoding IDHs are frequently mutated in a variety of human malignancies, including gliomas.Pentavalent 99mTc dimercaptosuccinic acid (99mTc (V) DMSA), is a nonspecific tumor targeting SPECT radiotracer, that has been used for imaging of various tumors including lung and breast carcinoma. However, to date, scarce reports discussed the utility of DMSA-V in patients with glioma.SPECT has the advantages of being widely available and not expensive. Multiple SPECT tracers have been explored. Of them Thallium-201 and 99 mTc-MIBI are, possibly, the most extensively discussed.
Conditions
- Brain Glioma
Sponsors & Collaborators
-
Assiut University
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-11-30
- Primary Completion
- 2023-11-30
- Completion
- 2023-12-31
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