Vorasidenib Expanded Access Program
NCT05592743 · Status: APPROVED_FOR_MARKETING · Type: EXPANDED_ACCESS
Last updated 2024-11-05
Summary
This is an expanded access program to provide vorasidenib for treatment of patients 12 years or older with IDH1- or IDH2-mutated glioma.
Conditions
- Glioma
- Recurrence
- Disease Attributes
- Pathologic Processes
- Neoplasms, Neuroepithelial
- Neuroectodermal Tumors
- Neoplasms, Germ Cell and Embryonal
- Neoplasms by Histologic Type
- Neoplasms
- Neoplasms, Glandular and Epithelial
- Neoplasms, Nerve Tissue
Interventions
- DRUG
-
Vorasidenib
Oral therapy
Sponsors & Collaborators
-
Servier Pharmaceuticals, LLC
collaborator UNKNOWN - lead INDUSTRY
Principal Investigators
-
Jonathan Dewey, MD · Servier Pharmaceuticals, LLC
Eligibility
- Min Age
- 12 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
More Related Trials
-
Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive IDH-1 Mutant Glioma
NCT05484622 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma
NCT01378481 ·Status: TERMINATED ·Phase: PHASE1
-
Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation
NCT07286292 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
NCT05588141 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
AMPLIFYing NEOepitope-specific VACcine Responses in Progressive Diffuse Glioma
NCT03893903 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation
NCT02481154 ·Status: COMPLETED ·Phase: PHASE1
-
ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas
NCT05609994 ·Status: RECRUITING ·Phase: PHASE1
-
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas
NCT01434602 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma
NCT04590664 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
NCT05303519 ·Status: RECRUITING ·Phase: PHASE3
-
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma
NCT05076513 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Trial of IDH305 in IDH1 Mutant Grade II or III Glioma
NCT02977689 ·Status: WITHDRAWN ·Phase: PHASE2
-
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma
NCT02704858 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment
NCT05859334 ·Status: RECRUITING ·Phase: PHASE2
-
G207 Followed by Radiation Therapy in Malignant Glioma
NCT00157703 ·Status: COMPLETED ·Phase: PHASE1
-
Sorafenib in Newly Diagnosed High Grade Glioma
NCT00884416 ·Status: COMPLETED ·Phase: PHASE1
-
Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
NCT00238303 ·Status: COMPLETED ·Phase: PHASE2
-
ERAS-801 for the Treatment of Resectable and Progressive or Recurrent IDH Wildtype Grade IV Glioblastoma or Astrocytoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial
NCT07089641 ·Status: RECRUITING ·Phase: PHASE1
-
Study of AG-120 and AG-881 in Subjects With Low Grade Glioma
NCT03343197 ·Status: COMPLETED ·Phase: PHASE1
-
Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype
NCT03718767 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma
NCT01547546 ·Status: COMPLETED ·Phase: PHASE1
-
EGFR Inhibition Using Weekly Erlotinib for Recurrent Malignant Gliomas
NCT01257594 ·Status: COMPLETED ·Phase: PHASE1
-
Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma
NCT01817751 ·Status: COMPLETED ·Phase: PHASE2
-
Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.
NCT04712721 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
AMG 595 First-in-Human in Recurrent Gliomas
NCT01475006 ·Status: COMPLETED ·Phase: PHASE1