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Restoring Neural Oscillatory Communication in Developmental Dyslexia

NCT05583136 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2025-01-27

No results posted yet for this study

Summary

Developmental dyslexia (DD) is a multifactorial disorder that hampers the education of about 10% of individuals across cultures and is associated to both phonological and visual deficits. The latter have been linked to a deficit in the magnocellular-dorsal (M-D) visual stream, that has a critical role in guiding the activity of ventral visual stream areas where letters identity is extracted. Here, we will test the efficacy of transcranial alternate current stimulation (tACS) of the M-D stream combined with reading trainings in adult participants with DD, assessing the neurophysiological underpinnings of these new trainings with EEG and fMRI/DTI.

Conditions

  • Developmental Dyslexia

Interventions

DEVICE

Parietal tACS combined with visuo-attentional training

Parietal tACS combined with visuo-attentional training

DEVICE

Sham (placebo) tACS combined with visuo-attentional training

Sham (placebo) tACS combined with visuo-attentional training

DEVICE

Sham (placebo) tACS combined with phonics training

Sham (placebo) tACS combined with phonics training

Sponsors & Collaborators

  • IRCCS Ospedale San Raffaele

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-12-14
Primary Completion
2024-12-23
Completion
2024-12-23

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05583136 on ClinicalTrials.gov