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Perioperative Methadone in Hip Fracture Patients

NCT05581901 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 31

Last updated 2023-04-18

No results posted yet for this study

Summary

Postoperative analgesic treatment needs to be improved. Numerous studies suggest that a single dose of Methadone given during surgery significantly ameliorates postoperative pain and reduces postoperative opioid consumption. Perioperative methadone is already used in isolated cases such as patients with chronic pain or patients with high morphine tolerance. However, it is not routinely used in the elderly and fragile, and there is insufficient reliable evidence on this treatment and population. Further investigation is highly relevant and necessary.

Conditions

  • Methadone
  • Pain, Post Operative
  • Pain, Postoperative
  • Analgesics, Opioid

Interventions

DRUG

Methadone (Dose1)

Dose: 0.10mg/kg

DRUG

Methadone (Dose 2)

Dose: 0.15mg/kg

DRUG

Methadone (Dose 3)

Dose 0.20mg/kg

Sponsors & Collaborators

  • University of Southern Denmark

    lead OTHER

Principal Investigators

  • Jesper Schønnemann · Hospital of Southern Denmark - Aabenraa

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
SEQUENTIAL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-12
Primary Completion
2023-03-23
Completion
2023-04-04

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05581901 on ClinicalTrials.gov