Somatostatin Receptor Imaging in NPC, EBV Related Cancers
NCT05581550 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2025-07-20
Summary
The study aims to describe the avidity of somatostatin receptors in locally advanced, metastatic and locally recurrent nasopharyngeal cancer (NPC) and to determine the proportion of NPC patients with high somatostatin receptor density that may benefit from future somatostatin targeted therapeutic trial plans. The investigators also aim to determine the presence of somatostatin receptors in other EBV related cancers.
Conditions
- Nasopharyngeal Cancer
- Epstein-Barr Virus Related Carcinoma
Interventions
- RADIATION
-
FDG-PET
Patients will be fasted for 6 hours prior to intravenous injection of 370MBq +/- 10% (18)F-fluorodeoxyglucose. Scanning will be performed at an interval of at least 60 minutes following the injection.
- RADIATION
-
Galium-68 DOTATATE
200MBq +/- 10% Galium-68 DOTATATE will be injected intravenously. Scanning will be performed approximately 60 minutes after the injection.
Sponsors & Collaborators
-
National Cancer Centre Research Fund
collaborator UNKNOWN -
National Cancer Centre, Singapore
lead OTHER
Principal Investigators
-
Wen Long Nei, MD · National Cancer Centre, Singapore
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-06-29
- Primary Completion
- 2025-07-17
- Completion
- 2025-07-17
Countries
- Singapore
Study Locations
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