Somatostatin Receptor Imaging in NPC, EBV Related Cancers

NCT05581550 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2025-07-20

No results posted yet for this study

Summary

The study aims to describe the avidity of somatostatin receptors in locally advanced, metastatic and locally recurrent nasopharyngeal cancer (NPC) and to determine the proportion of NPC patients with high somatostatin receptor density that may benefit from future somatostatin targeted therapeutic trial plans. The investigators also aim to determine the presence of somatostatin receptors in other EBV related cancers.

Conditions

  • Nasopharyngeal Cancer
  • Epstein-Barr Virus Related Carcinoma

Interventions

RADIATION

FDG-PET

Patients will be fasted for 6 hours prior to intravenous injection of 370MBq +/- 10% (18)F-fluorodeoxyglucose. Scanning will be performed at an interval of at least 60 minutes following the injection.

RADIATION

Galium-68 DOTATATE

200MBq +/- 10% Galium-68 DOTATATE will be injected intravenously. Scanning will be performed approximately 60 minutes after the injection.

Sponsors & Collaborators

  • National Cancer Centre Research Fund

    collaborator UNKNOWN
  • National Cancer Centre, Singapore

    lead OTHER

Principal Investigators

  • Wen Long Nei, MD · National Cancer Centre, Singapore

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-29
Primary Completion
2025-07-17
Completion
2025-07-17

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05581550 on ClinicalTrials.gov