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Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty

NCT05572307 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2023-03-08

No results posted yet for this study

Summary

Single-celled sequencing for evaluating differences in gene expression patterns in different cell types of the dynamics of a means of this research as a starting point, to study the postoperative delirium and chronic pain at the cellular level changes the contents of a cell, reveal its occurrence and development of the role of gene regulation, find targets and biomarkers, and to provide new ideas for its pathogenesis, To provide theoretical basis support for its prevention, clinical diagnosis and treatment.

Conditions

  • Postoperative Delirium
  • Chronic Postsurgical Pain

Sponsors & Collaborators

  • The Affiliated Hospital of Xuzhou Medical University

    collaborator OTHER

  • Xuzhou Central Hospital

    lead OTHER

Principal Investigators

  • Yangzi Zhu, Doctor · Xuzhou Central Hospital

  • Liwei Wang, Doctor · Xuzhou Central Hospital

  • Junli Cao, Doctor · Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University

  • Daqing Ma, Doctor · Imperial College London, Chelsea and Westminster Hospital

Eligibility

Min Age
65 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-10-30
Primary Completion
2023-10-30
Completion
2023-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05572307 on ClinicalTrials.gov