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Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative

NCT05565079 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2026-02-10

No results posted yet for this study

Summary

24 patients will be treated with a coronally positioned tunnel with AlloDerm RTM with or without the addition of Enamel Matrix Derivative to compare the baseline and 6-month changes in recession defect coverage, clinical attachment levels, amount of keratinized tissue width, and soft tissue thickness.

Conditions

  • Recession, Gingival

Interventions

BIOLOGICAL

Regenerative tissue matrix and enamel matrix derivative

Subjects in this group will receive a coronally positioned tunnel with a regenerative tissue matrix (AlloDerm, RTM) and a porcine-derived enamel matrix derivative (Emdogain).

BIOLOGICAL

Regenerative tissue matrix

Subjects in both groups will receive a coronally positioned tunnel with a regenerative tissue matrix (AlloDerm, RTM).

Sponsors & Collaborators

  • University of Louisville

    lead OTHER

Principal Investigators

  • Bindu Dukka, BDS, MSD, MPH · Director, Graduate Periodontics, University of Louisville

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-10-06
Primary Completion
2024-10-07
Completion
2024-10-30
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05565079 on ClinicalTrials.gov