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Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients

NCT05561920 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 55

Last updated 2026-03-31

Study results available
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Summary

The treatment of advanced laryngeal cancer involves the removal of the entire larynx. After removal of the larynx, the pharyngoesophageal segment (PES) is created by reconstructing the soft tissue of the pharynx and oesophagus, and its vibration creates a substitute voice. High-speed video endoscopy (HSV) is the only method that visualises and measures the vibration of the PES after a laryngectomy. The acoustic characteristics of three forms of rehabilitated voice of laryngectomised individuals (oesophageal voice, tracheoesophageal (TE) voice using a voice prosthesis and electrolarynx) have been satisfactorily described, but the interdependence of acoustic and visual representations of the phonatory movement of the PES is still insufficiently studied. In recent years, biomechanical models have been developed to analyse the vibration of the PES, but consistent results have not yet been obtained that would explain whether the parameters from the analysis of the waveform of the PES can be compared with the parameters obtained from the acoustic analysis of the voice of a laryngectomised patient.Effective rehabilitation focuses on optimising speech and swallowing, which leads to a good integration of the laryngectomised person into society. One step towards achieving this goal is a thorough assessment of their voice and communication experiences, as well as analysing the phonatory movements of the PES using HSV technology.

Conditions

  • Larynx Cancer
  • Laryngectomy; Status

Interventions

DEVICE

High-speed video endoscopy (HSV)

Describe anatomical and morphological characteristics o phonatory movement of pharyngoesophageal segment (PES) in laryngectomy patients

DEVICE

Acoustic voice analysis

acoustic program (lingWAVES - Voice and speech analyser) - measuring the values of acoustic parameters in voice recordings

BEHAVIORAL

Quality of life questionnaire

Filling out questionnaires

Sponsors & Collaborators

  • Josip Juraj Strossmayer University of Osijek

    collaborator OTHER

  • Osijek University Hospital

    lead OTHER

Principal Investigators

  • Ana Đanić Hadžibegović, Assoc. Prof · Clinical Hospital Centre Zagreb

  • Andrijana Včeva, Full Prof · University Hospital Osijek

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-01
Primary Completion
2025-04-01
Completion
2025-04-01

Countries

  • Croatia

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05561920 on ClinicalTrials.gov