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Diagnosis of Laryngeal Lesions Using the Probe-based Confocal Laser Endomicroscopy

NCT04139889 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2020-01-07

No results posted yet for this study

Summary

To evaluate the diagnosis of laryngeal lesions using the Probe-based Confocal Laser Endomicroscopy in vivo.

Conditions

  • Laryngeal Leiomyoma
  • Probe-based Confocal Laser Endomicroscopy

Interventions

DIAGNOSTIC_TEST

Confocal Laser Endomicroscopy

Confocal laser microendoscopy (CLE) as a new non-invasive imaging technique can be used for "optical biopsy", which can perform real-time microscopic information of tissue in vivo at cellular level with resolutions up to 1μm and magnifications up to 1000 times. CLE is now being increasingly used with very promising results in gastroenterology, especially in the diagnostic investigation of Barret's esophagus, stomach cancer, colorectal cancer and various lesions of the biliary tract. With an intravenous injection of fluorescein, probe-based CLE (pCLE: GastroFlex probe with the Cellvizio laser system, Mauna Technologies, Paris, France) allows us to view the interstitial spaces, cells, and small capillaries in a window of 240 μm and to a depth of 60 μm.

Sponsors & Collaborators

  • Eye & ENT Hospital of Fudan University

    lead OTHER

Principal Investigators

  • Huawei Li, PhD &MD · Otorhinolaryngology Department of Eye & ENT Hospital, Fudan University

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-01
Primary Completion
2019-11-30
Completion
2020-12-21

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04139889 on ClinicalTrials.gov