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Identification of Breath Biomarkers in Esophageal Cancer

NCT05557955 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 210

Last updated 2023-11-18

No results posted yet for this study

Summary

Neoadjuvant chemoradiotherapy (CRT) followed by surgery or definitive CRT is the standard treatment for locally advanced esophageal squamous cell carcinoma (ESCC), but the clinical outcomes are not satisfactory. Breathomics testing is a promising, non-invasive, simple method for detection and screening for ESCC. This observational study aimed to role of exhaled volatile organic compounds (VOCs) in predicting the efficacy and risk of recurrence in patients with locally advanced ESCC who received CRT.

Conditions

Interventions

OTHER

Breathing test

Dynamic breathing testing will be performed before, during, and after radiotherapy. Volatile organic compounds (VOCs) will be collected.

Sponsors & Collaborators

  • Mian XI

    lead OTHER

Principal Investigators

  • Ruihua Xu, MD · Sun Yat-sen University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-27
Primary Completion
2023-10-31
Completion
2023-11-15

Countries

  • China

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05557955 on ClinicalTrials.gov