F-Tryptophan PET/CT in Human Cancers
NCT05556473 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2026-01-23
Summary
Imaging procedures such as 1-(2-\[18F\]FLUOROETHYL)-L-Tryptophan PET/CT in patients with cancers may help doctors assess a patient's response to treatment and help plan the best treatment in the future. The purpose is to see if there can be a better differentiation of tumor and non-tumor tissue where the tumor tissue has a higher uptake of Tryptophan.
Conditions
- Intracranial Glioma
- Metastatic Brain Tumor
- Breast Cancer
- Neuroendocrine Tumors
- Rectal Cancer
Interventions
- DRUG
-
1-(2-[18F]FLUOROETHYL)-L-Tryptophan
Radioactive tracer 1-(2-\[18F\]FLUOROETHYL)-L-Tryptophan 0.14mCi/kg/5MBq/kg injection given one time prior to PET Scan.
Sponsors & Collaborators
-
Washington University School of Medicine
collaborator OTHER -
Barbara Ann Karmanos Cancer Institute
lead OTHER
Principal Investigators
-
Csaba Juhasz, M.D.,Ph.D · Barbara Ann Karmanos Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-09-29
- Primary Completion
- 2027-12-31
- Completion
- 2027-12-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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